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  1. Nair, G, Jain, V. An intramolecular crosstalk in D29 mycobacteriophage endolysin governs the lytic cycle and phage-host population dynamics. Sci. Adv. 2024, 10: eadh9812. (Abstract)

  2. Wani, SR, Jain, V. Deciphering the molecular mechanism and regulation of formaldehyde detoxification in Mycobacterium smegmatis. Appl. Environ. Microbiol. 2024, 90: e02039-23. (Abstract)

  3. Singh, AK, Gangakhedkar, R, Thakur, HS, Raman, SK, Patil, SA, Jain, V. Mycobacteriophage D29 Lysin B exhibits promising antimycobacterial activity against drug-resistant Mycobacterium tuberculosis. Microbiol. Spectr. 2023, 11: e0459722. (Abstract)

  4. Abdelrahman, F, Gangakhedkar, R, Nair, G, El-Didamony, G, Askora, A, Jain, V, El-Shibiny, A. Pseudomonas phage ZCPS1 endolysin as a potential therapeutic agent. Viruses. 2023, 15: 520. (Abstract)

  5. Wani, SR, Dubey, AA, Jain, V. Ms6244 is a novel Mycobacterium smegmatis TetR family transcriptional repressor that regulates cell growth and morphophysiology. FEBS Lett. 2023, 597: 1428-1440. (Abstract)

  6. Mulye, M, Singh, MI, Jain, V. From Processivity to Genome Maintenance: The Many Roles of Sliding Clamps. Genes 2022, 13: 2058. (Abstract)

  7. Seniya, SP, Jain, V. Decoding phage resistance by mpr and its role in survivability of Mycobacterium smegmatis. Nucleic Acids Res. 2022, 50: 6938-6952. (Abstract)

  8. George, A, Ravi, R, Tiwari, PB, Srivastava, SR, Jain, V, Mahalakshmi, R. Engineering a Hyperstable Yersinia pestis Outer Membrane Protein Ail Using Thermodynamic Design. J. Am. Chem. Soc. 2022, 144: 1545-1555 (Abstract)

  9. James, S, Jain, V. A positive selection Escherichia coli recombinant protein expression vector for one-step cloning. Front. Bioeng. Biotechnol. 2022, 9: 776828. (Abstract)

  10. Wani, SR, Jain, V. Molecular dissection of a dedicated formaldehyde dehydrogenase from Mycobacterium smegmatis. Protein Sci. 2022, 31: 628-638. (Abstract)

  11. Patil, V, Jain, V. Understanding metabolic remodelling in Mycobacterium smegmatis to overcome energy exigency and reductive stress under energy-compromised state. Front. Microbiol. 2021, 12: 722229. (Abstract)

  12. Bavda, VR, Yadav, A, Jain, V. Decoding the molecular properties of mycobacteriophage D29 Holin provides insights into Holin engineering. J. Virol. 2021, 95: e02173-20. (Abstract)

  13. Nair, G, Jain, V. Separation of Mycobacterium smegmatis from a mixed culture using the cell wall binding domain of D29 mycobacteriophage endolysin. Front. Microbiol. 2020, 11: 1119. (Abstract)

  14. Bavda, VR, Jain, V. Deciphering the role of holin in mycobacteriophage D29 physiology. Front. Microbiol. 2020, 11: 883. (Abstract)

  15. Seniya, SP, Yadav, P, Jain, V. Construction of E. coli—Mycobacterium shuttle vectors with a variety of expression systems and polypeptide tags for gene expression in mycobacteria. PLoS One. 2020, 15(3): e0230282. (Abstract)

  16. Patil, V, Jain, V. Insights into the physiology and metabolism of a mycobacterial cell in an energy-compromised state. J. Bacteriol. 2019, 201: e00210-19. (Abstract)

  17. Dubey, AA, Jain, V. Mycofactocin is essential for the establishment of methylotrophy in Mycobacterium smegmatis. Biochem. Biophys. Res. Commun. 2019, 516: 1073-1077. (Abstract)

  18. Joshi, H, Nair, G, Gangakhedkar, R, Jain, V. Understanding the role of lysozyme-like domain of the D29 mycobacteriophage-encoded endolysin in the host cell lysis and phage propagation. Microbiology 2019, 165: 1013-1023. (Abstract)

  19. Dubey, AA, Jain, V. MnoSR is a bona fide two-component system involved in methylotrophic metabolism in Mycobacterium smegmatis. Appl. Environ. Microbiol. 2019, 85: e00535-19. (Abstract)

  20. Dubey, AA, Wani, SR, Jain, V. Methylotrophy in mycobacteria: Dissection of the methanol metabolism pathway in Mycobacterium smegmatis. J. Bacteriol. 2018, 200: e00288-18. (Abstract)

  21. Joshi, H, Seniya, SP, Suryanarayanan, V, Patidar, ND, Singh, SK, Jain, V. Dissecting the Structure-function Relationship in Lysozyme Domain of Mycobacteriophage D29-encoded Peptidoglycan Hydrolase. FEBS Lett. 2017, 591: 3276-3287. (Abstract)

  22. Singh, MI, Jain, V. Identification and characterization of an inside-out intermediate in the folding pathway of bacteriophage sliding clamp. Biophys. J. 2017, 113: 1738-1749. (Abstract)

  23. Mahalakshmi, R, Maurya, SR, Burdak, B, Surti, P, Patel, MS, Jain, V. Structural plasticity of T4 transcription co-activator gp33 revealed by a protease-resistant unfolded state. Biochem. Biophys. Res. Commun. 2017, 492: 61-66. (Abstract)

  24. Joshi, H, Jain, V. Novel method to rapidly and efficiently lyse Escherichia coli for the isolation of recombinant protein. Anal. Biochem. 2017, 528: 1-6. (Abstract)

  25. Kamilla, S, Jain, V. Robust high throughput real-time monitoring assay for the specific screening of bacterial cell envelope inhibitors. Proc. Indian Natn. Sci. Acad. 2017, 83: 211-215. (Abstract)

  26. Singh, MI, Ganesh, B, Jain, V. On the domains of T4 phage sliding clamp gp45: an intermolecular crosstalk governs structural stability and biological activity. Biochim. Biophys. Acta 2017, 1861: 3300-3310. (Abstract)

  27. Dubey, AA, Singh, MI, Jain, V. Rapid and robust PCR-based all-recombinant cloning methodology. PLoS One 2016, 11(3): e0152106. (Abstract)

  28. Singh, MI, Jain, V. Molecular dissection of the homotrimeric sliding clamp of T4 phage: Two domains of a subunit display asymmetric characteristics. Biochemistry 2016, 55(3): 588-596. (Abstract)

  29. Lella, M, Kamilla, S, Jain, V, Mahalakshmi, R. Molecular mechanism of holin transmembrane domain I in pore formation and bacterial cell death. ACS Chem. Biol. 2016, 11: 910-920. (Abstract)

  30. Kamilla, S, Jain, V. Mycobacteriophage D29 holin C-terminal region functionally assists in holin aggregation and bacterial cell death. FEBS J. 2016, 283(1): 173-190. (Abstract)

  31. Pohane, AA, Jain, V. Insights into the regulation of bacteriophage endolysin: Multiple means to the same end. Microbiology 2015, 161: 2269-2276. (Abstract)

  32. Syal, K, Joshi, H, Chatterji, D, Jain, V. Novel pppGpp binding site at the C-terminal region of Rel enzyme from Mycobacterium smegmatis. FEBS J. 2015, 282(19): 3773-3785. (Abstract)

  33. Pohane, AA, Patidar, ND, Jain, V. Modulation of domain-domain interaction and protein’s function by a charged linker: A case study of mycobacteriophage D29 endolysin. FEBS Lett. 2015, 589(6): 695-701. (Abstract)

  34. Sharma, A, Pohane, AA, Bansal, S, Bajaj, A, Jain, V, Srivastava, A. Cell Penetrating Synthetic Antimicrobial Peptides (SAMPs) Exhibiting Potent and Selective Killing of Mycobacterium by Targeting its DNA. Chem. Eur. J. 2015, 21(9): 3540-3545. (Abstract)

  35. Ekal, L, Ganesh, B, Joshi, H, Lama, L, Jain, V. Evidence of a conserved intrinsically disordered region in the C-terminus of the stringent response protein Rel from mycobacteria. FEBS Lett. 2014, 588: 1839-1849. (Abstract)

  36. Pohane, AA, Joshi, H, Jain, V. Molecular dissection of phage endolysin: An interdomain interaction confers host specificity in Lysin A of Mycobacterium phage D29. J. Biol. Chem. 2014, 289: 12085-12095. (Abstract)

  37. Singh, MI, Jain, V. Tagging the Expressed Protein with 6 Histidines: Rapid Cloning of an Amplicon with Three Options. PLoS ONE 2013, 8(5): e63922. (Abstract)

  38. Twist, K, Campbell, EA, Deighan, P, Nechaev, S, Jain, V, Geiduschek, EP, Hochschild, A, Darst, SA. Crystal structure of the bacteriophage T4 late-transcription co-activator gp33 with the β-subunit flap domain of E. coli RNA polymerase. Proc. Natl. Acad. Sci. USA 2011, 108(50): 19961-19966. (Abstract)

  39. Jain, V, Saleem-Batcha, R, Chatterji, D. Synthesis and hydrolysis of pppGpp in mycobacteria: a ligand mediated conformational switch in Rel. Biophys. Chem. 2007, 127(1-2): 41-50. (Abstract)

  40. Jain, V, Saleem-Batcha, R, China, A, Chatterji, D. Molecular dissection of the mycobacterial stringent response protein Rel. Protein Sci. 2006, 15(6): 1449-1464. (Abstract)

  41. Jain, V, Kumar, M and Chatterji, D. ppGpp: Stringent response and survival. J. Microbiol. 2006, 44(1): 1-10. (Abstract)

  42. Jain, V, Sujatha, S, Ojha, AK, Chatterji, D. Identification and characterization of rel promoter element of Mycobacterium tuberculosis. Gene 2005, 351: 149-157. (Abstract)

  43. Sivakumar, P, Sharmila, P, Jain, V, Saradhi, PP. Sugars have potential to curtail oxygenase activity of Rubisco. Biochem. Biophys. Res. Commun. 2002, 298: 247-250. (Abstract)
 
 
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