Publications

• Jain M., Tripathi A., Emmanuel M., Verma K., Datta S. (2020) Molecular Insights into E. histolytica Mediated Host Tissue Invasion. In: Guillen N. (eds) Eukaryome Impact on Human Intestine Homeostasis and Mucosal Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-44826-4_19
   
• EhC2B, a C2 domain-containing protein, promotes erythrophagocytosis in Entamoeba histolytica via actin nucleation. Aashutosh Tripathi, Megha Jain, Mintu Chandra, Sameena Parveen, Rupali Yadav,    Brett M. Collins, Sankar Maiti, Sunando Datta, PLoS Pathog. 2020

 

• SNX27-retromer Assembly Recycles MT1-MMP to Invadopodia and Promotes Breast Cancer Metastasis. Priyanka Sharma  , Sameena Parveen  , Lekha V Shah , Madhumita Mukherjee  , Yannis Kalaidzidis , Anthony J Kozielski  , Roberto Rosato, Jenny C Chang , Sunando Datta. J Cell Biol 2020
• Rab GTPases take centre stage in understanding Entamoeba histolytica biology. Kuldeep Verma, Vijay Kumar Srivastava & Sunando Datta, Small GTPases 2018

 

• Atypical Switch-I Arginine plays a catalytic role in GTP hydrolysis by Rab21 from Entamoeba histolytica. Kotyada C, et al. Biochem Biophys Res Commun 2018

 

• Heavy subunit of cell surface Gal/GalNAc lectin (Hgl) undergoes degradation via endo-lysosomal compartments in Entamoeba histolytica.Verma K, Datta S. Small GTPases 2017

 

• Essential and selective role of SNX12 in transport of endocytic and retrograde cargo.Priya A, Sugatha J, Parveen S, Lacas-Gervais S, Raj P, Gilleron J, Datta S. Journal of Cell Science 2017

 

• Structural and thermodynamic characterization of metal binding in Vps29 from Entamoeba histolytica: Implication in retromer function.Srivastava VK, Yadav R, Natsuki W, Tomar P, Mukherjee M, Gourinath S, Nakada-Tsukui K, Nozaki T, Datta S. Molecular Microbiology. 2017

 

• The monomeric GTPase Rab35 regulates phagocytic cup formation and phagosomal maturation in Entamoeba histolytica. Verma K, Datta S. Journal of Biological Chemistry. 2017 Jan

 

• Role of EhRab7A in phagocytosis of type 1 fimbriated E. coli by Entamoeba histolytica. Verma K, Nozaki T, Datta S. Mol Microbiol. 2016 Oct

 

• Biophysical studies on calcium and carbohydrate binding to carbohydrate recognition domain of Gal/GalNAc lectin from Entamoeba histolytica: insights into host cell adhesion. Yadav R, Verma K, Chandra M, Mukherjee M, Datta S. J Biochem. 2016 Sep

 

• Role of cysteine residues in the redox-regulated oligomerization and nucleotide binding to EhRabX3. Chandra M, Datta S. Mol Biochem Parasitol. 2016 Aug

 

• Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1. Chandra M, Saran R, Datta S. Biochem Biophys Res Commun. 2016 Apr

 

• Crystal Structure Analysis of Wild Type and Fast Hydrolyzing Mutant of EhRabX3, a Tandem Ras Superfamily GTPase from Entamoeba histolytica. Srivastava VK, Chandra M, Nakano YS, Nozaki T, Datta S. J Mol Biol. 2016 Jan

 

• Insights into endosomal maturation of human holo-transferrin in the enteric parasite Entamoeba histolytica: essential roles of Rab7A and Rab5 in biogenesis of giant early endocytic vacuoles. Verma K, Nakano YS, Nozaki T, Datta S. Cell Microbiol. 2015 Dec
• Small GTPase Rab21 mediates fibronectin induced actin reorganization in Entamoeba histolytica: implications in pathogen invasion. Emmanuel M, Nakano YS, Nozaki T, Datta S. PLOS Pathogen. 2015 Mar

 

• Molecular insights into Rab7-mediated endosomal recruitment of core retromer: deciphering the role of Vps26 and Vps35. Priya A, Kalaidzidis I, Kalaidzidis Y, Lambright D, Datta S. Traffic. 2015 Jan

 

• Crystallization and preliminary X-ray analysis of RabX3, a tandem GTPase from Entamoeba histolytica. Srivastava V, Chandra M, Datta S. Acta Crystallogr F Struct Biol Commun. 2014 Jul

 

• Insights into the GTP/GDP cycle of RabX3, a novel GTPase from Entamoeba histolytica with tandem G-domains. Chandra M, Mukherjee M, Srivastava V, Nakano YS, Nozaki T, Datta S. Biochemistry, 2014

 

• New players in the same old game: a system level in silico study to predict type III secretion system and effector proteins in bacterial genomes reveals common themes in T3SS mediated pathogenesis. Sadarangani V, Datta S and Arunachalam M. BMC Research Notes, 2013

 

• Identification of the switch in early-to-late endosome transition.Poteryaev D, Datta S, Ackema K, Zerial M and Spang A. Cell, 2010 Apr 30;141(3):497-508..(Co- First Author).

 

• GTP-binding-defective forms of tissue transglutaminase trigger cell death. Datta S, Antonyak MA, Cerione RA. Biochemistry. 2007 Dec 25;46(51):14819-29. Epub 2007 Dec 1.

 

• Snapshots of RecA protein involving movement of the C-domain and different conformations of the DNA-binding loops: crystallographic and comparative analysis of 11 structures of Mycobacterium smegmatis RecA. Krishna R, Prabu JR, Manjunath GP, Datta S, Chandra NR, Muniyappa K, Vijayan M. J Mol Biol. 2007 Apr 6;367(4):1130-44.

 

• Importance of Ca(2+)-dependent transamidation activity in the protection afforded by tissue transglutaminase against doxorubicin-induced apoptosis. Datta S, Antonyak MA, Cerione RA. Biochemistry. 2006 Nov 7;45(44):13163-74.
• Crystal structures of Mycobacterium smegmatis RecA and its nucleotide complexes. Datta S, Krishna R, Ganesh N, Chandra NR, Muniyappa K, Vijayan M. J Bacteriol. 2003 Jul;185(14):4280-4.

 

• Structural studies on MtRecA-nucleotide complexes: insights into DNA and nucleotide binding and the structural signature of NTP recognition. Datta S, Ganesh N, Chandra NR, Muniyappa K, Vijayan M. Proteins. 2003 Feb 15;50(3):474-85.

 

• The effect of stabilizing additives on the structure and hydration of proteins: a study involving tetragonal lysozyme. Datta S, Biswal BK, Vijayan M. Acta Crystallogr D Biol Crystallogr. 2001 Nov ;57(Pt 11):1614-20. Epub 2001 Oct 25.

 

• Crystal structures of Mycobacterium tuberculosis RecA and its complex with ADPAlF(4): implications for decreased ATPase activity and molecular aggregation. Datta S, Prabu MM, Vaze MB, Ganesh N, Chandra NR, Muniyappa K, Vijayan M. Nucleic Acids Res. 2000 Dec 15;28(24):4964-73.

 

• Use of propensities of amino acids to the local structural environments to understand effect of substitution mutations on protein stability. Reddy BV, Datta S, Tiwari S. Protein Eng. 1998 Dec;11(12):1137-45.

 

• Analysis of structural environment of Amino Acids that alter in vitro protein stability. Reddy BVB and Datta S J. Biomol. Str. Dyn. 1997 14: 772